Higher Degree by Research Application Portal

TitleValorising CO2-derived acetate into biopolymers using synthetic biology
SupervisorA/Pro Heng Chooi
Dr Georg Fritz
KeywordsCarbon valorisation
Synthetic biology
Fungi
Research areaBiological Sciences
Project description

The PhD project will be part of a 4-year project funded by the Australian Research Council Linkage Project scheme. The project seeks to establish the basis for building a ‘CO2 foundry’, encompassing the electrochemical conversion of CO2 into a C2 intermediate, which serves as a feedstock for the subsequent bioconversion into value-added platform chemicals and biopolymers, using engineered microbes. The PhD project will focus on the metabolic engineering of fungal strains for the production of simple and longer chain dicarboxylic acids, using acetate (derived from CO2 electrocatalysis) as the feedstock. This can include rational genome engineering as well as adaptive and directed evolution. Another aspect would be the optimisation of fermentation conditions using contemporary bioprocess engineering methods.

Opportunity statusClosed
Open date18 Aug 2023
Close date31 Jan 2024
Funding source

ARC Linkage Project and UWA co-funding scholarship scheme

SchoolSchool of Molecular Sciences
Contact

Contact Heng Chooi, yitheng.chooi@uwa.edu.au or Georg Fritz, georg.fritz@uwa.edu.au

Specific project requirement

- A Bachelor Degree with a background in biochemistry, biotechnology, biological sciences or a related discipline.
- An Honours or Master degree that includes a minimum one-year research project and dissertation.
- Background in metabolic engineering, synthetic biology, and molecular biology as well as experience in analytical (bio)chemistry is desirable.

Duration3.5 years

Guidance

Please submit your interest to the project supervisors Heng Chooi yitheng.chooi@uwa.edu.au and Georg Fritz georg.fritz@uwa.edu.au

Please include a copy of your CV that includes your recent grades and English test results.

Please also states why you are interested in the project.

Open now (Aug 2023) till March 2024. You can send us your query anytime.

- A Bachelor Degree with a background in biochemistry, biotechnology, biological sciences or a related discipline.

- An Honours or Master degree that includes a minimum one-year research project and dissertation.

Valorising CO2-derived acetate into biopolymers using synthetic biology