Higher Degree by Research Application Portal

TitleControlling Neisseria disease
SupervisorProf Charlene Kahler
CourseDoctor of Philosophy
KeywordsNeisseria meningitidis
Neisseria gonorrhoeae
Research areaHealth Sciences
Project description

Neisseria meningitidis, the causative agent of epidemic meningitis, is a significant public health burden worldwide causing 1.2 million cases per year globally, with an estimated fatality rate of 10% (WHO). There are a variety of meningococcal vaccines targeting serogroups A, B, C, W, Y.

My research has focussed on the following aspects of N. meningitidis

1. Genomic epidemiology of N. meningitidis during outbreaks of invasive meningococcal disease in Western Australia.

2. The evolution of N. meningitidis in response to vaccination.

3. Dissecting the regulatory networks which control the pathogenesis of this pathogen.

This program includes techniques covering basic microbiology skills, molecular biology techniques (cloning, mutation, sequencing, PCR (both detection and real-time) and bioinformatics.

Opportunity statusOpen
Open date28 Jul 2024
SchoolGraduate Research School
Contact

Contact:

Charlene.kahler@uwa.edu.au

Specific project requirement

Students are advised that they should have completed a Bachelor of Science majoring in Microbiology OR a major in Biomedical science with at least three units covering Microbiology and Molecular Biology.

Course typeDoctorates
Description

The Doctor of Philosophy (PhD) is a program of independent, supervised research that is assessed solely on the basis of a thesis, sometimes including a creative work component, that is examined externally. The work presented for a PhD must be a substantial and original contribution to scholarship, demonstrating mastery of the subject of interest as well as an advance in that field of knowledge. 

Visit the course webpage for full details of this course including admission requirements, course rules and the relevant CRICOS code/s.

Duration4 years

Guidance